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    Related terms
    • Brand Names: U.S.: Americaine® Hemorrhoidal [OTC];Anbesol® Baby [OTC];Anbesol® Cold Sore Therapy [OTC];Anbesol® Jr. [OTC];Anbesol® Maximum Strength [OTC];Anbesol® [OTC];Benzodent® [OTC];Bi-Zets [OTC];Boil-Ease® Pain Relieving [OTC];Cepacol® FizzlersT [OTC];Cepacol® Sore Throat & Coating [OTC];Cepacol® Sore Throat Plus Coating Relief [OTC];Cepacol® Sore Throat [OTC];Cepacol® Ultra Sore Throat [OTC];Chiggerex® Plus [OTC];ChiggerTox® [OTC];Dent's Extra Strength Toothache Gum [OTC];Dentapaine [OTC];Dermoplast® Antibacterial [OTC];Dermoplast® Pain Relieving [OTC];Detane® [OTC];Foille® [OTC];HDA® Toothache [OTC];HurriCaine ONET;Hurricaine® [OTC];Ivy-Rid® [OTC];Kank-A® Soft Brush [OTC];Lanacane® Maximum Strength [OTC];Lanacane® [OTC];Little Teethers® [OTC];Medicone® Hemorrhoidal [OTC];Mycinettes® [OTC];Orabase® with Benzocaine [OTC];Orajel® Baby Daytime and Nighttime [OTC];Orajel® Baby Teething Nighttime [OTC];Orajel® Baby Teething [OTC];Orajel® Cold Sore [OTC];Orajel® Denture Plus [OTC];Orajel® Maximum Strength [OTC];Orajel® Medicated Mouth Sore [OTC];Orajel® Medicated Toothache [OTC];Orajel® Mouth Sore [OTC];Orajel® Multi-Action Cold Sore [OTC];Orajel® PM Maximum Strength [OTC];Orajel® Ultra Mouth Sore [OTC];Orajel® [OTC];Outgro® [OTC];Red CrossT Canker Sore [OTC];Rid-A-Pain Dental [OTC];Sepasoothe® [OTC];Skeeter Stik® [OTC];Sore Throat Relief [OTC];Sting-Kill® [OTC];Tanac® [OTC];Thorets [OTC];Trocaine® [OTC];Zilactin® Tooth & Gum Pain [OTC];Zilactin®-B [OTC]
    • Brand Names: Canada: Anbesol® Baby;Zilactin Baby®;Zilactin-B®

    • It is used to treat signs of hemorrhoids or rectal irritation.
    • It is used to ease the pain caused by sunburn and skin irritation.
    • It is used to ease pain from a toothache, sore throat, or canker sore.
    • It is used to numb an area of the skin before care.
    • Benzocaine numbs the nerves where it is used.


    How to take

    • Skin:
    • Do not take this drug by mouth. Use on your skin only. Keep out of your mouth, nose, and eyes (may burn).
    • Wash your hands before and after use.
    • Clean affected part before use. Make sure to dry well.
    • Put a thin layer on the affected skin and rub in gently.
    • If you are using the spray for your face, spray it on your hand or gauze and then put it on your face.
    • Oral:
    • Do not swallow this drug unless told to do so by your doctor.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take 2 doses at the same time or extra doses.
    • Do not change the dose or stop this drug. Talk with the doctor.


    • Store at room temperature.
    • Protect from heat.



    • If you have an allergy to benzocaine or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
    • If you have a skin infection.


    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Use care when a large part of the skin is involved or where there are open wounds.
    • Do not eat while your mouth feels numb. You may bite your tongue.
    • Do not use coverings (bandages, dressings, make-up) unless told to do so by your doctor.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.
    • Oral spray:
    • If you have heart disease, talk with your doctor.
    • If you have lung disease, talk with your doctor.
    • If you smoke, talk with your doctor.

    Side Effects

    • Skin irritation.


    • Change in the health problem being treated. Is it better, worse, or about the same?

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Trouble breathing.
    • A fast heartbeat.
    • Big change in balance.
    • Weakness, numbness, or tingling.
    • Change in thinking clearly and with logic.
    • Very bad skin irritation.
    • Any rash.
    • Side effect or health problem is not better or you are feeling worse.
    • Oral spray:
    • Blue or gray skin color, headache, dizziness, trouble breathing, feeling tired or weak, and/or a fast heartbeat.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs may be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. If in the U.S., you may also call the FDA at 1-800-FDA-1088 or if in Canada, you may also call Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

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    • Copyright © 1978-2013 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (

    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.